New product idea Essay Example | Topics and Well Written Essays - 2250 words

New product idea - Essay Example he possibility to easily consume your daily dose of fresh fruit juice at work, at school, †¦ Fruitness offers a small assortment of orange-based fruit juices to match everyone’s taste and it makes for the perfect refreshment during a break from working. The exclusivity of our business model lies in the concept of delivering fresh juices directly to companies. Fruitness will be established as a B.V.B.A. to limit liabilities for the owners. The money that has to be raised to start the business is â‚ ¬ 60.000, financed by five managers. Dividends will not be paid during the first 7 years. Profit will be re-invested in the company to finance internal growth. Some of our major direct competitors are Minute Maid (Coca Cola Co.) and Tropicana (Pepsi Co.). Their main advantages are their size and expertise. Their weakness is their disability to deliver a fresh juice to the market. â€Å"Fruitness provides a solution to increased awareness towards health and better-for-you products. All Fruitness juices are daily made with fresh fruit and delivered within 24 hours. Fruitness’ innovative business model ensures that Fruitness is available at the places where people spend most of their time and energy; at work or at school!† Fruitness produces fresh orange juice, squeezed the first day and directly delivered to the customer the second day. It is made of 100% fresh fruit, without addition of sugar, concentrate, preservatives or use of heat. The packaging consists of a white HDPE (high density polyethylene) bottle that helps maintain high Vitamin C levels (extra 15% retention rate over clear bottles). It is a high quality product aimed at health-conscious consumers. The juice is delivered to companies that want to provide their employees with a fresh, healthy and tasty alternative to the usual soft-drinks. To meet customer demand and taste, Fruitness produces different flavours. It focuses on citrus juices, all with an orange basis: Orange ² (100% orange), Orange & Lime

Why is the trafficking of naive lymphocytes important Outline the Essay

Why is the trafficking of naive lymphocytes important Outline the stages in the development of the specific immune respons - Essay Example Our bodies are both fragile and resilient at the same time; being so soft and easily broken, yet keeping us alive even during the worst of conditions, always adapting and always surviving. One of the important factors that keep us alive is our immune system and its ability to adapt to the environment and the pathogens it contains. According to Gene Mayer, PhD, there are two ways wherein the body can protect itself from infection: Innate or nonspecific immune system, and Adaptive or specific immune system. ‘The innate immune system is the first line of defense’ which provides immediate, but nonspecific responses to infection (e.g. skin, mucus, tears, sneezing, etc.). The adaptive immune system is slower and responds only to specific antigens with cells called lymphocytes. Once the adaptive immune system responds to a specific antigen, the body will remember it and will produce antibodies to combat the antigen more effectively every time it comes back.1 There are two main types of lymphocytes involved in adaptive immunity--B lymphocytes (B cells) and T lymphocytes (T cells). These cells are produced in the bone marrow. One of the differences between the two is that the T cells have to migrate to the thymus gland to mature. Stein and Nombela-Arrieta (2005, pp.1-12) state that these lymphocytes that have just matured and have yet to encounter an antigen, are called naive lymphocytes. From the bone marrow and the thymus, the lymphocytes are then trafficked through the bloodstream to the secondary lymphoid organs (SLO), which are the peripheral and mesenteric lymph nodes, spleen and gut-associated lymphoid tissues called the Peyer's patches. In the SLO, once the naive cells encounter antigens and become activated, they will undergo changes and will eventually leave to combat the infection.2 Kuby wrote that when a pathogen enters the body, it enters the bloodstream and is transported to the lymph nodes and lymphatic organs where antigen presenting cells ( APCs) break it down into antigen compounds to be bound to Major Histocompatibility Complex (MHC) molecules. The naive helper T cells become activated once they encounter the antigen bound to the MHC molecules. It then becomes an effector cell (Th) that produces cytokines which activate B cells, T cells, macrophages and other cells included in the specific immune response. Once the Th cells are released into the bloodstream, when they find the antigen, they secrete their cytokines. T cytotoxic cells (Tc) become another effector cell called the cytotoxic T lymphocyte (CTL). This kind of effector cell does not produce cytokines but is designed to destroy infected cells. Once the B cells encounter the antigen, they proliferate and differentiate into antibody-secreting plasma cells whose antibodies attach to the antigen, effectively neutralizing it. Other B cells turn into memory B cells that allow for a faster response to illness once the same pathogen enters the body again.3 Mayer and Nyland (2010) pointed out that ‘since there are relatively few T or B lymphocytes with a receptor for any particular antigen (1/10,000 – 1/100,000), the chances for a successful encounter between an antigen and the appropriate lymphocyte are slim.’4 The chances of encountering the right antigen with the right antibody are maximized with recirculation to the SLOs. The lymphocytes constantly circulate from the lymph organs to the blood via lymphatics if there is no antigen present. ‘It is estimated that 1-2% of lymphocytes recirculate every hour’ (Mayer & Nyland, 2010).5 If it does encounter an antigen, the cells differentiate into the effector cells (B, Th, or Tc) to combat the infection. After the infection, it can go back to the blood stream